CYP450 Protein Assay - Human Induction Kit
The CYP450 Protein Assay - Human Induction Kits, use an LC/mass spectrometry workflow to enable direct measurement of protein expression changes of individual CYP450 isoforms with high specificity, sensitivity, and accuracy. These kist have been developed to employ MRM analysis to quantify the protein levels of seven key CYP450 protein isoforms for induction studies: 1A2, 2B6, 2C9, 2C19, 2E1, 3A4 and 3A5. Both a four isoform (1A2, 2B6, 3A4 and 3A5) and a seven isoform ( 1A2, 2B6, 2C9, 2C19, 2E1, 3A4 and 3A5) kit are available.
- Directly measure CYP450 induction at the protein level without expensive antibodies
- Measure individual CYP450 isoforms with high specificity, sensitivity, and accuracy
- Easy-to-use kits and method employ a common MRM workflow
- Results are equivalent to traditional mRNA or activity assays