iMethod Application for Melamine and Cyanuric Acid in Milk Products Version 1.0 for Cliquid Software

For research use only. Not for use in diagnostic procedures.

Determine melamine and cyanuric acid in milk using solid phase extraction (SPE) cleanup and fast LC/MS/MS analysis 

Recent issues with melamine contamination in wheat gluten- and milk-based ingredients from China have highlighted the need for both food manufacturers and regulatory agencies to utilize fast and accurate analytical techniques like LC-MS/MS to proactively ensure product safety.  This verified method for melamine and cyanuric acid analysis in milk samples utilizes a single solid phase extraction (SPE) cleanup step to remove matrix components for determination by LC-MS/MS with a run time of less than 10 minutes and limits of quantitation below 1 μg/kg.

Two MRMs are used per compound with ion ratios calculated to provide an extra degree of confirmation.

To learn more, please view this flyer: A Rapid iMethod™ Application for the Analysis of Melamine and Cyanuric Acid in Milk Products

iMethod Application for Melamine and Cyanuric Acid in Milk Products Version 1.0 for Cliquid Software

Overview

Reduce development time

ActivityUsing an iMethod ApplicationTraditional Method Development
Complete Test Protocol DocumentationIncludedWeeks–Months
Sample Prep TechniquesIncluded, with examples and referencesWeeks–Months
Optimized MS/MS Acquisition ParametersIncludedWeeks–Months
LC Instrument Parameters with Retention TimesIncludedDays–Weeks
Integration (Quantitation) ParametersIncludedDays
Reporting TemplatesIncludedDays
LC/MS/MS Library SpectraMay be included. Stand-alone libraries are also available.Weeks–Months
Staff Training – SoftwareSimple Cliquid® Software interface, no additional trainingTraditional MS Software and review procedures – Days
Method ValidationWeeks. Validation templates and support availableWeeks–Months
Complete Test Development and DeploymentWeeks6–12 months