Biomarker quantitation

Explore the potential of trusted LC-MS/MS solutions designed to simplify and accelerate biomarker quantitation. Bring drug candidates through the development pipeline more efficiently and confidently with accurate results obtained using innovative hardware and software, lab-tested methods and expert support.

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Overview

No matter where you are in the drug development process, SCIEX supports your analytical workflows with LC-MS solutions on a single software platform.
Discover innovative instruments and software with robust and sensitive performance for enabling new discoveries.

Workflow

Small biomarkers

Our systems provide in-depth coverage that enables you to characterize and confidently quantify biomarkers, even low abundant ions. With different technology options for specific needs, SCIEX can help you get the answers you need.

  • Achieve confident answers in hours instead of days
  • Confidently characterize and quantify small biomarkers with robust, sensitive analyses
  • Improve workflows with support from our dependable team of experts

Small biomarkers

Solution

Suited for:
  • Targeted panel assays
  • Absolute sensitivity
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Small biomarkers

Solution

Suited for:
  • Easily identifying and quantifying unknown analytes
  • Analyzing even difficult-to-fragment analytes with alternative fragmentation technology
  • Exploring complex matrices and samples with higher selectivity needs
Request info
Request info

Featured resources

Filter:
High sensitivity quantitation of acylcarnitines using the SCIEX 7500 system

Learn how to achieve high sensitivity and reproducibility with a simple sample preparation method and a fast LC gradient with 8 carnitine and acylcarnitine biomarkers monitored in rat plasma.

Sensitive bioanalysis of galactosyl sphingosine (GalSPH) and glucosyl sphingosine (GluSPH) in cerebral spinal fluid

Sensitivity for 2 glycosphingolipids (GluSPH and GalSPH) was evaluated in cerebral spinal fluid using the SCIEX 7500 system. An assay was developed using HILIC chromatography along with positive MRM analysis and electrospray ionization. Calibration curves were generated on the SCIEX 7500 system and the QTRAP 6500+ system to assess the sensitivity difference.

Identification and quantitation of lipid biomarkers using accurate mass spectrometry

We demonstrate a combination of qualitative and quantitative workflows to identify and quantify lipid biomarkers in a mouse brain matrix.

Workflow

Large biomarkers

Discover better analytical solutions that meet your needs for in-depth coverage with robust and sensitive performance. Confidently characterize and quantify large-molecule biomarkers—including low-abundant ions—faster than ever before with easy-to-use, integrated software. All of our solutions are complemented by dependable access to an expert support team eager to help you improve your workflows and move promising candidates forward.

  • Achieve confident answers in hours instead of days
  • Confidently characterize and quantify large biomarkers with robust, sensitive analyses
  • Supported by dependable service support

Large biomarkers

Solution

Suited for:
  • Easily identifying and quantifying unknown analytes
  • Analyzing even difficult-to-fragment analytes with alternative fragmentation technology
  • Exploring complex matrices and samples with higher selectivity needs
Request info
Request info

Large biomarkers

Solution

Suited for:
  • Targeted panel assays
  • Absolute sensitivity
Request info
Request info

Featured resources

Sensitive multiplexed quantitation of protein biomarkers for early drug discovery and development

Dive into a new solution for highly sensitive quantitation of surfactant proteins in human plasma at a signature peptide level with low-ng/mL lower limits of quantitation.

All resources

Filter:
High sensitivity quantitation of acylcarnitines using the SCIEX 7500 system

Learn how to enable high sensitivity and reproducibility with a simple sample preparation method and a fast LC gradient with 8 carnitine and acylcarnitine biomarkers monitored in rat plasma.

Sensitive bioanalysis of galactosyl sphingosine (GalSPH) and glucosyl sphingosine (GluSPH) in cerebral spinal fluid

Sensitivity for 2 glycosphingolipids (GluSPH and GalSPH) was evaluated in cerebral spinal fluid using the SCIEX 7500 system. An assay was developed using HILIC chromatography along with positive MRM analysis and electros

Identification and quantitation of lipid biomarkers using accurate mass spectrometry

We demonstrate a combination of qualitative and quantitative workflows to identify and quantify lipid biomarkers in a mouse brain matrix.

Sensitive multiplexed quantitation of protein biomarkers for early drug discovery and development

Dive into a new solution for highly sensitive quantitation of surfactant proteins in human plasma at a signature peptide level with low-ng/mL lower limits of quantitation.

Associated applications

Biomarker discovery

Confidently discover, quantify and translate previously inaccessible and challenging biomarkers with solutions designed to facilitate in-depth, comprehensive analysis.

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