Lipids are the unsung heroes of metabolism. They participate in a number of diverse processes, such as cell membrane integrity, energy transportation, cell signaling and mediation of host immune response to viral infections. A prerequisite to this functional diversity and specificity is substantial structural diversity, which makes conventional metabolomics workflows unfit for studying lipids.
SCIEX solutions are designed to help tackle the many challenges related to detecting, fully characterizing and quantifying the diversity of lipid species across the lipidome. For lipid analysis, the ZenoTOF 7600 system equipped with electron activated dissociation (EAD) technology enables full characterization of lipid species all within a single experiment. The speed and sensitivity of the SCIEX 7500 system enable large-scale targeted assays to be performed to quantify large numbers of structural lipids and lipid mediators in a single run. The power of the SelexION device adds an orthogonal strategy for the separation of different lipid classes with the ability to differentiate isobaric and isomeric species. See how simple, integrated LC-MS solutions can allow core labs and translational researchers to interrogate lipid profiles and reveal lipid species alterations that occur in metabolic disorders such as diabetes, obesity, hypertension, stroke and atherosclerosis.
Explore the uncharted realms of the lipidome. Learn about methodologies and solutions for identifying new and unknown lipids and comparatively quantifying complex samples.
Set your sights on specific lipids. Use highly sensitive and specific approaches to quantify lipids and map biological changes across large numbers of samples.
Get qualitative flexibility combined with quantitative power. The ZenoTOF 7600 system represents a crucial step change in MS/MS technology with EAD and provides a new level of power for characterizing the lipidome.
Quantify lipids with the SCIEX 7500 system, which offers high sensitivity and a wide linear dynamic range that is ideal for large-scale targeted quantification.
A new dimension in selectivity through lipid class separation provides more confident identification and better quantification. Differential ion mobility also enables isoelemental and isobaric separation within lipid classes to help improve quantification results.
Discover a detection and quantification workhorse with a wide range of workflows for lipid analysis. Answer the toughest biological questions with quantitative MRM and MRM3, qualitative QTRAP scans, the SelexION device and the ability to mix and match in a single run.
Whether it is an infusion MS/MSALL shotgun approach or an LC-MS SWATH acquisition workflow, DIA workflows from SCIEX find more.
Associate Professor, Head Metabolomics Group, Leiden University Medical Center (LUMC)
Researcher, RIKEN Center for Sustainable Resource Science, Metabolome Informatics Research Team & RIKEN Center for Integrative Medical Sciences, Laboratory for Metabolomics
State Key Laboratory of Molecular and Developmental Biology, Chinese Academy of Sciences, Beijing
Discover innovative metabolomics solutions that can help get you closer to your phenotype.
Learn about large-scale omics profiling from field to fork and beyond. Explore a comprehensive approach to food and nutrition analysis.
The authenticity of food products such as alcohol, fruit juice, meat, olive oil, spices and more is crucial to consumer confidence and brand protection.